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- Title
The use of random effects models to allow for clustering in individually randomized trials.
- Authors
Lee, Katherine J; Thompson, Simon G
- Abstract
We describe different forms of clustering that may occur in individually randomized trials, where the observed outcomes for different individuals cannot be regarded as independent. We propose random effects models to allow for such clustering, across a range of contexts and trial designs, and investigate their effect on estimation and interpretation of the treatment effect.
- Publication
Clinical trials (London, England), 2005, Vol 2, Issue 2, p163
- ISSN
1740-7745
- Publication type
Journal Article
- DOI
10.1191/1740774505cn082oa