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- Title
CAR T-Cell Therapy: Update on the State of the Science.
- Authors
Lamprecht, Misty; Dansereau, Colleen
- Abstract
Chimeric antigen receptor (CAR) T-cell therapy leverages the power of the patient's own immune system by serving as a bridge to connect genetically modified T cells to the surface antigens of tumor cells based on targeted ligands. Clinical trials have demonstrated compelling overall response and survival rates in individuals with B-cell malignancies. The current approved agents target CD19, an antigen commonly overexpressed in B-cell hematologic and other malignancies.
- Publication
Clinical journal of oncology nursing, 2019, Vol 23, Issue 2, p6
- ISSN
1538-067X
- Publication type
Journal Article
- DOI
10.1188/19.CJON.S1.6-12