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- Title
Chemotherapy-induced peripheral neuropathy: a review and implications for oncology nursing practice.
- Authors
Wickham, Rita
- Abstract
Advances in supportive care have increased the likelihood that previously less common adverse effects of chemotherapy will be more evident. The incidence of chemotherapy-induced peripheral neuropathy (CIPN) is increasing because more neurotoxic drugs have been developed and because patients are living longer and receiving multiple chemotherapy regimens. This article reviews the anatomy of the peripheral nervous system, the proposed mechanisms of CIPN, and manifestations of CIPN from vinca alkaloids, taxanes, and platinum analogs. Major topics of this article are evidence-based data regarding symptom management, a review of medical management, and a synthesis of nursing care for patients at risk for or experiencing CIPN.
- Publication
Clinical journal of oncology nursing, 2007, Vol 11, Issue 3, p361
- ISSN
1092-1095
- Publication type
Journal Article
- DOI
10.1188/07.CJON.361-376