Works matching DE "PHARMACEUTICAL chemistry"

Results: 5000

Mechanism of Salvia miltiorrhiza in the treatment of periodontitis: integrative analyses via network pharmacology, molecular dynamics, and cellular assays.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-05040-4

By:

Chen, Yabing;
Du, Siyu;
Guo, Yijing;
Zheng, Yi;
Wang, Lei

Publication type:

Article

Synthetic Approaches to 1,3,4-Oxadiazole-Containing Boronic Derivatives.

Published in:

Applied Sciences (2076-3417), 2025, v. 15, n. 14, p. 8054, doi. 10.3390/app15148054

By:

Wołek, Barbara;
Kudelko, Agnieszka

Publication type:

Article

Researchers on why DEA should reject HHS cannabis rescheduling recommendations.

Published in:

Brown University Child & Adolescent Psychopharmacology Update, 2025, v. 27, n. 8, p. 4, doi. 10.1002/cpu.30994

By:

Knopf, Alison

Publication type:

Article

Machine learning-driven bioavailability prediction in early-stage drug development: a KNIME-based computational workflow for digital health applications.

Published in:

Xenobiotica, 2025, v. 55, n. 5, p. 339, doi. 10.1080/00498254.2025.2508804

By:

Hammami, Majdi;
Yeddes, Walid;
Gadhoumi, Hamza;
Yazidi, Raghda;
Saidani Tounsi, Moufida;
Msaada, Kamel

Publication type:

Article

Aprovechamiento de biomasa y residuos agrícolas en la producción de moléculas plataforma: ácido levulínico y derivados.

Published in:

Ciencia en Desarrollo, 2025, v. 16, n. 1, p. 135, doi. 10.19053/uptc.01217488.v16.n1.2025.18188

By:

Escobar Caicedo, María Angélica;
Emilia Pérez, María;
Palermo, Valeria;
Gabriel Sathicq, Ángel;
Pablo Romanelli, Gustavo

Publication type:

Article

Anti-Obesity Effect of Liposomal Suspension and Extracts of Hibiscus sabdariffa and Zingiber officinale in a Murine Model Fed a Hypercaloric Diet.

Published in:

Nutrients, 2025, v. 18, n. 14, p. 2275, doi. 10.3390/nu17142275

By:

Palomo-Martínez, Luis Edwardo;
Paniagua-Castro, Norma;
Escalona-Cardoso, Gerardo Norberto;
Leyva-Daniel, Diana E.;
Ibañez-Hernández, Miguel A. A.;
Cruz-Narvaez, Yair;
Alamilla-Beltrán, Liliana

Publication type:

Article

Editorial for the Special Issue "Mathematical Modelling in Drug Delivery".

Published in:

2025

By:

Jónsdóttir, Fjóla

Publication type:

Editorial

AQbD Approach Applied to NIR in a Complex Topical Formulation: Bifonazole as Case Study.

Published in:

Pharmaceutics, 2025, v. 17, n. 7, p. 835, doi. 10.3390/pharmaceutics17070835

By:

Chiarentin, Lucas;
Moura, Vera;
Pais, Alberto A. C. C.;
Vitorino, Carla

Publication type:

Article

Development and Validation of a New LC-MS/MS Method for Simultaneous Quantification of Ivacaftor, Tezacaftor and Elexacaftor Plasma Levels in Pediatric Cystic Fibrosis Patients.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 7, p. 1028, doi. 10.3390/ph18071028

By:

Mancini, Alessandro;
Simeoli, Raffaele;
Cristiani, Luca;
Cairoli, Sara;
Ciciriello, Fabiana;
Boni, Alessandra;
Alghisi, Federico;
Rossi, Chiara;
Antonetti, Giacomo;
Vici, Carlo Dionisi;
Fiocchi, Alessandro Giovanni;
Cutrera, Renato;
Goffredo, Bianca Maria

Publication type:

Article

Study on the Pharmacological Efficacy and Mechanism of Dual-Target Liposome Complex AD808 Against Alzheimer's Disease.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 7, p. 977, doi. 10.3390/ph18070977

By:

Liu, Chang;
Wang, Xiaoqing;
Xu, Wei;
Yu, Songli;
Zhang, Yueru;
Xu, Qiming;
Tan, Xiangshi

Publication type:

Article

Diversity-oriented synthesis of novel benzo[h]quinoline and pyrimidine-tethered tri-substituted methane using L-proline as an effective bio-organo-catalyst.

Published in:

Journal of the Iranian Chemical Society, 2025, v. 22, n. 7, p. 1453, doi. 10.1007/s13738-025-03237-5

By:

Alizadeh, Sajedeh;
Esmaeili, Abbas Ali

Publication type:

Article

Front Cover: Streamlining Vorinostat Synthesis: A Chemoenzymatic Continuous Flow Approach (Eur. J. Org. Chem. 27/2025).

Published in:

European Journal of Organic Chemistry, 2025, v. 28, n. 27, p. 1, doi. 10.1002/ejoc.202582701

By:

Annunziata, Francesca;
Tamborini, Lucia;
Pinto, Andrea;
Christodoulou, Michail S.;
Dallavalle, Sabrina;
Princiotto, Salvatore;
Contente, Martina L.

Publication type:

Article

CALB Immobilized on Octyl-Agarose—An Efficient Pharmaceutical Biocatalyst for Transesterification in Organic Medium.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 14, p. 6961, doi. 10.3390/ijms26146961

By:

Siódmiak, Joanna;
Dulęba, Jacek;
Kocot, Natalia;
Mastalerz, Rafał;
Haraldsson, Gudmundur G.;
Siódmiak, Tomasz

Publication type:

Article

In Silico Evaluation of Quinolone–Triazole and Conazole–Triazole Hybrids as Promising Antimicrobial and Anticancer Agents.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 14, p. 6752, doi. 10.3390/ijms26146752

By:

Suha, Humaera Noor;
Almatarneh, Mansour H.;
Poirier, Raymond A.;
Uddin, Kabir M.

Publication type:

Article

Evaluation of oral silymarin formulation efficacy in prevention of doxorubicin induced hepatotoxicity in patients with non-metastatic breast cancer.

Published in:

Journal of Oncology Pharmacy Practice, 2025, v. 31, n. 6, p. 965, doi. 10.1177/10781552241268778

By:

Fatemi Shandiz, Ashkan;
Karimi, Gholamreza;
Dayyani, Mahdiyeh;
Hosseini, Sare;
Elyasi, Sepideh

Publication type:

Article

Sanguinarine Inhibits Gastric Cancer Progression by Targeting the NOS2/SOD1 Axis to Promote Ferroptosis.

Published in:

American Journal of Chinese Medicine, 2025, v. 53, n. 5, p. 1545, doi. 10.1142/S0192415X25500594

By:

Feng, Zhaotian;
Luan, Muhua;
Zhu, Wenshuai;
Xing, Yuanxin;
Ma, Xiaoli;
Wang, Yunshan;
Jia, Yanfei

Publication type:

Article

Puerarin Attenuates Myocardial Ischemia-Reperfusion Damage by Targeting Ferroptosis through 14-3-3η Modulation.

Published in:

American Journal of Chinese Medicine, 2025, v. 53, n. 5, p. 1501, doi. 10.1142/S0192415X25500570

By:

Qiao, YaMei;
Lai, SongQing;
Wang, YaRu;
Hu, FaJia;
Liu, Yue;
Zhai, FeiXiang;
Zhang, ZeYu;
Liu, Dan;
Huang, Huang

Publication type:

Article

Advances and Perspectives on the Anti-Fibrotic Mechanisms of the Quercetin.

Published in:

American Journal of Chinese Medicine, 2025, v. 53, n. 5, p. 1411, doi. 10.1142/S0192415X25500545

By:

Liu, Xiaoqin;
Liang, Qingzhi;
Qin, Yufeng;
Chen, Zhengtao;
Yue, Rensong

Publication type:

Article

Chinese Medicine for Non-Alcoholic Fatty Liver Disease: Targeting Key Signaling Pathways.

Published in:

American Journal of Chinese Medicine, 2025, v. 53, n. 5, p. 1379, doi. 10.1142/S0192415X25500533

By:

Zheng, Shihao;
Shi, Xinyue;
Xue, Chengyuan;
Wang, Qiuyue;
Qi, Wenying;
Li, Xiaoke;
Du, Hongbo;
Li, Size;
Zao, Xiaobin;
Zhang, Peng;
Ye, Yongan

Publication type:

Article

Novel Curcumin Floating Tablets for Spatial Delivery in Peptic Ulcer.

Published in:

BioMed Research International, 2025, v. 2025, p. 1, doi. 10.1155/bmri/6622146

By:

Gupta, Chitra;
Sahu, Girdhar Kumar;
Parashar, Ashish Kumar;
Singh, Kalpana;
Bukke, Sarad Pawar Naik;
Udom, Godswill James;
Banerjee, Baisakhi

Publication type:

Article

Synthesis of benzo[f]indole-4,9-dione derivatives by multicomponent reactions (microreview).

Published in:

2025

By:

Parvin, Tasneem

Publication type:

Abstract

PROTAC : Nouvelles stratégies thérapeutiques basées sur l'exploitation des voies de dégradation des protéines.

Published in:

Biologie Aujourd'hui, 2024, v. 218, n. 3/4, p. 105, doi. 10.1051/jbio/2024010

By:

Cornu, Marie;
Lemaitre, Thomas;
Schwalen, Florian;
Kieffer, Charline;
Voisin-Chiret, Anne Sophie

Publication type:

Article

Analysis and mining of L-ornithine L-aspartate adverse events based on FAERS database.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-12420-w

By:

Zhang, Hui;
Song, Chaoqun;
Zhao, Dexi;
Lin, Minghao;
Fu, Yujuan

Publication type:

Article

Exploring QSPR in breast cancer drugs via entire neighborhood indices and regression models.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-12179-0

By:

Altassan, Alaa;
Saleh, Anwar;
Alashwali, Hanaa;
Hamed, Marwa;
Muthana, Najat

Publication type:

Article

Imine Reductase–Catalyzed Remote Stereocontrol for Enantiodivergent Synthesis of Cyclohexylidene‐Based Axially Chiral Amines.

Published in:

Angewandte Chemie, 2025, v. 137, n. 30, p. 1, doi. 10.1002/ange.202500572

By:

Li, Keting;
Liu, Zhen;
Wang, Bin;
Huang, Ling;
Yu, Luyao;
Zhou, Zitian;
Lin, Liang;
Fang, Pengfei;
Fu, Haigen

Publication type:

Article

Isolation of Secondary Metabolites of Rhaponticum carthamoides (Willd.) Iljin and Assessment of Their Antiplatelet Activity.

Published in:

Pharmaceutical Chemistry Journal, 2025, v. 59, n. 3, p. 324, doi. 10.1007/s11094-025-03395-z

By:

Pronin, N. A.;
Whaley, A. K.;
Whaley, A. O.;
Kuz'mina, S. A.;
Rukoyatkina, N. I.;
Gambaryan, S. P.

Publication type:

Article

Prospects for Using 1,2,3-Triazole Derivatives in Medicinal Chemistry.

Published in:

Pharmaceutical Chemistry Journal, 2025, v. 59, n. 3, p. 285, doi. 10.1007/s11094-025-03390-4

By:

Kukov, D. V.;
Dronov, A. I.;
Frolova, M. A.;
Afanasyeva, I. S.;
Chernykh, I. V.

Publication type:

Article

Qu-zhuo-tong-bi decoction exerts gouty arthritis therapy by skewing macrophage polarization through butanoate metabolism.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01162-6

By:

Song, Siyue;
Wen, Xianghui;
Chen, Fusen;
Li, Jiatao;
Shi, Kaiyue;
Lou, Yu;
Xu, Anyi;
Wen, Chengping;
Shao, Tiejuan

Publication type:

Article

Nurses Perspectives on Low-Dose Methadone for Pain in Nursing Homes: Semi-structured Interviews.

Published in:

Journal of Palliative Medicine, 2025, v. 28, n. 7, p. 893, doi. 10.1089/jpm.2024.0551

By:

Holler O'Brien, Jennifer;
Baldwin, Caroline;
Burns, Jenica;
Kleckner, Amber;
Uemura, Takeshi

Publication type:

Article

Harnessing Visible Light: Photocatalyzed Green Routes to Complex Heterocycles (2019–2024).

Published in:

Asian Journal of Organic Chemistry, 2025, v. 14, n. 7, p. 1, doi. 10.1002/ajoc.202400703

By:

Deshwal, Nidhi;
Dhankhar, Jyoti;
Kaushik, Himanshu;
Malmir, Masoume;
Chandra, Ramesh;
Sperry, Jonathan;
Singh, Snigdha

Publication type:

Article

Recent Synthetic Strategies for the Functionalization of Indole and Azaindole Scaffolds.

Published in:

Asian Journal of Organic Chemistry, 2025, v. 14, n. 7, p. 1, doi. 10.1002/ajoc.202400694

By:

Annie, Aksa S;
Pradeep Kumar, Marappan;
Adithya, Ramesh;
Vignesh, Kaliswaran;
Dhayalan, Vasudevan

Publication type:

Article

Atroposelective construction of axially chiral alkenylindole-fused nine-membered rings via catalytic asymmetric formal (4 + 5) cycloaddition.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-62035-y

By:

Liu, Si-Jia;
Wang, Xue;
Yang, Ji-Xiang;
Ao, Xian-Song;
Ni, Shao-Fei;
Zhang, Yu-Chen;
Shi, Feng

Publication type:

Article

Nanotechnology for Targeted Rheumatoid Arthritis Therapy: Innovations and Challenges.

Published in:

Journal of Inflammatory Diseases, 2025, v. 29, n. 2, p. 1, doi. 10.69107/jid-162710

By:

Nikfarjam, Bahareh Abd;
Hajiaghayi, Mehri

Publication type:

Article

Medicinal Chemistry of Kinase Inhibitors: A Review of Recent Advances.

Published in:

Cuestiones de Fisioterapia, 2025, v. 54, n. 3, p. 292

By:

Shinymol;
Kuumar, Pushpendra;
Singh, Sakshi;
Kashyap, Manoj;
Kumar, Shivam;
Ambhore, Shraddha Sunil;
Asokan, Neethu;
Rani, Rekha

Publication type:

Article

Dual Photoredox/Copper‐Catalyzed 1,2‐Diphosphorothiolation of Alkenes with P(O)SH Compounds to Access Vicinal Bisphosphorothioates.

Published in:

Chinese Journal of Chemistry, 2025, v. 43, n. 16, p. 1977, doi. 10.1002/cjoc.70089

By:

Zhang, Pengbo;
Wang, Longyu;
Guo, Xinyi;
Liu, Yaxin;
Yang, Qihang;
Gao, Xia

Publication type:

Article

Natural Coumarin‐Hybridized Thiazolylbenzonitriles as New Structural Scaffolds to Exert Potentially Multitargeting Supramolecular Antibacterial Behavior.

Published in:

Chinese Journal of Chemistry, 2025, v. 43, n. 16, p. 1909, doi. 10.1002/cjoc.70072

By:

Li, Qian‐Yue;
Zeng, Chun‐Mei;
Chen, Yao;
Ahmad, Nisar;
Zhang, Shao‐Lin;
Zhou, Cheng‐He

Publication type:

Article

Direct C–H Fluorination of N-Heterocycles Promoted by Transition Metals in High Oxidation State.

Published in:

Russian Journal of Organic Chemistry, 2025, v. 61, n. 6, p. 1180, doi. 10.1134/S1070428025602080

By:

Gryaznova, T. V.;
Kholin, K. V.;
Tarasov, M. V.;
Gavrilova, E. L.;
Budnikova, Yu. H.

Publication type:

Article

Synthetic Approaches to Heterocyclic Scaffolds: 4-Thiazolidinone Derivatives as Heterocyclic Scaffolds: Synthesis and Biological Activity (A Review).

Published in:

Russian Journal of Organic Chemistry, 2025, v. 61, n. 5, p. 765, doi. 10.1134/S1234567824604856

By:

Thakkar, Jay;
Vaghani, Hasit;
Kardani, Hit;
Patel, Prachi

Publication type:

Article

Advancing Pharmaceutical Security: Noninvasive Detection of Falsified Vaccines and Drugs Using wNMR.

Published in:

Pharmaceutical Research, 2025, v. 42, n. 6, p. 987, doi. 10.1007/s11095-025-03880-w

By:

Taraban, Marc B.;
Briggs, Katharine T.;
Karki, Pratima;
Grunin, Leonid;
Yu, Y. Bruce

Publication type:

Article

A piperidinyl indole derivative, potential complement factor B inhibitor, plays a renoprotective role in diabetic nephropathy.

Published in:

Diabetic Medicine, 2025, v. 42, n. 8, p. 1, doi. 10.1111/dme.70092

By:

Li, Zi‐Han;
Sun, Zi‐Jun;
Chang, Dong‐Yuan;
Zhao, Ming‐Hui;
Tang, Sydney C. W.;
Chen, Min

Publication type:

Article

Multicolored sequential resonance energy transfer for detection of simultaneous ligand binding at G protein-coupled receptors.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61690-5

By:

Valentini, Alice;
Dibnah, Bethany;
Ciba, Marija;
Duncan, Elaine M.;
Manandhar, Asmita;
Strellis, Bethany;
Vita, Luca;
Lucianno, Olivia;
Massey, Conor;
Coe, Sophie;
Ulven, Trond;
Hudson, Brian D.;
Rexen Ulven, Elisabeth

Publication type:

Article

Cartilage-protective effects of lopinavir/ritonavir: in vitro and in silico exploration of the HIF-1α/SOX9/IL-1β pathway.

Published in:

Journal of Orthopaedic Surgery & Research, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13018-025-06068-5

By:

Ozbek, Hanefi;
Yilmaz, Ibrahim;
Akyuz, Aslı;
Pehlivanoglu, Suray;
Sirin, Duygu Yasar;
Albayrak, Mehmet;
Yilmaz, Omer Faruk

Publication type:

Article

New alkyl triphenylphosphonium dipterocarpol derivatives with cytotoxicity against the MCF-7 breast cancer cell line.

Published in:

Journal of Computer-Aided Molecular Design, 2025, v. 39, n. 1, p. 1, doi. 10.1007/s10822-025-00631-2

By:

Tran, Tu H.;
Le, Tho H.;
Nguyen, Thu-Ha T.;
Vong, Long B.;
Nguyen, Mai T. T.;
Nguyen, Nhan T.;
Dang, Phu H.

Publication type:

Article

Photoinduced Copper‐Mediated Difluoroalkylation of Arylsulfonium Salts with XCF<sub>2</sub>COR.

Published in:

Chemistry - An Asian Journal, 2025, v. 20, n. 13, p. 1, doi. 10.1002/asia.202500331

By:

Xia, Fang;
Wang, Yan‐Hao;
Ding, Xing‐Yu;
Zhang, Cheng‐Pan

Publication type:

Article

Milestones in cheminformatics.

Published in:

Journal of Cheminformatics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13321-025-01054-9

By:

Martinez-Mayorga, Karina;
Medina-Franco, José L.

Publication type:

Article

GPCR-A17 MAAP: mapping modulators, agonists, and antagonists to predict the next bioactive target.

Published in:

Journal of Cheminformatics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13321-025-01050-z

By:

Caniceiro, Ana B.;
Amorim, Ana M. B.;
Rosário-Ferreira, Nícia;
Moreira, Irina S.

Publication type:

Article

Catalytic Activity Alternation of an Artificial Metalloenzyme by Switchable Binding to the Proteins.

Published in:

ChemCatChem, 2025, v. 17, n. 13, p. 1, doi. 10.1002/cctc.202500154

By:

Muguruma, Kyohei;
Imai, Kyosuke;
Tanaka, Katsunori

Publication type:

Article

Integrated Multi-Omics Analysis Reveals the Regulatory Mechanism of Peanut Skin Procyanidins on Lipid Metabolism in High-Fat-Diet-Induced Obese Mice.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2228, doi. 10.3390/nu17132228

By:

Shen, Jinxin;
Zhou, Yi;
Yang, Daijun;
Liu, Ruonan;
Zhu, Xiaoling;
Liu, Rui

Publication type:

Article

Postbiotics Formulation and Therapeutic Effect in Inflammation: A Systematic Review.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2187, doi. 10.3390/nu17132187

By:

Zdybel, Kinga;
Śliwka, Angelika;
Polak-Berecka, Magdalena;
Polak, Paweł;
Waśko, Adam

Publication type:

Article

Hydrazides as Powerful Tools in Medicinal Chemistry: Synthesis, Reactivity, and Biological Applications.

Published in:

Molecules, 2025, v. 30, n. 13, p. 2852, doi. 10.3390/molecules30132852

By:

Teixeira, Sofia;
Castanheira, Elisabete M. S.;
Carvalho, M. Alice

Publication type:

Article