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- Title
Multilevel competing risk models to evaluate the risk of nosocomial infection.
- Authors
Wolkewitz, Martin; Cooper, Ben S; Palomar-Martinez, Mercedes; Alvarez-Lerma, Francisco; Olaechea-Astigarraga, Pedro; Barnett, Adrian G; Harbarth, Stephan; Schumacher, Martin
- Abstract
Risk factor analyses for nosocomial infections (NIs) are complex. First, due to competing events for NI, the association between risk factors of NI as measured using hazard rates may not coincide with the association using cumulative probability (risk). Second, patients from the same intensive care unit (ICU) who share the same environmental exposure are likely to be more similar with regard to risk factors predisposing to a NI than patients from different ICUs. We aimed to develop an analytical approach to account for both features and to use it to evaluate associations between patient- and ICU-level characteristics with both rates of NI and competing risks and with the cumulative probability of infection.
- Publication
Critical care (London, England), 2014, Vol 18, Issue 2, pR64
- ISSN
1466-609X
- Publication type
Journal Article
- DOI
10.1186/cc13821