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- Title
Persistent organ dysfunction plus death: a novel, composite outcome measure for critical care trials.
- Authors
Heyland, Daren K; Muscedere, John; Drover, John; Jiang, Xuran; Day, Andrew G; Canadian Critical Care Trials Group
- Abstract
Due to resource limitations, few critical care interventions have been rigorously evaluated with adequately powered randomized clinical trials (RCTs). There is a need to improve the efficiency of RCTs in critical care so that more definitive high quality RCTs can be completed with the available resources. The objective of this study was to validate and demonstrate the utility of a novel composite outcome measure, persistent organ dysfunction (POD) plus death, for clinical trials of critically ill patients.
- Publication
Critical care (London, England), 2011, Vol 15, Issue 2, pR98
- ISSN
1466-609X
- Publication type
Journal Article
- DOI
10.1186/cc10110