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- Title
HER2 and ESR1 mRNA expression levels and response to neoadjuvant trastuzumab plus chemotherapy in patients with primary breast cancer.
- Authors
Denkert, Carsten; Huober, Jens; Loibl, Sibylle; Prinzler, Judith; Kronenwett, Ralf; Darb-Esfahani, Silvia; Brase, Jan C; Solbach, Christine; Mehta, Keyur; Fasching, Peter A; Sinn, Bruno V; Engels, Knut; Reinisch, Mattea; Hansmann, Martin-Leo; Tesch, Hans; von Minckwitz, Gunter; Untch, Michael
- Abstract
Recent data suggest that benefit from trastuzumab and chemotherapy might be related to expression of HER2 and estrogen receptor (ESR1). Therefore, we investigated HER2 and ESR1 mRNA levels in core biopsies of HER2-positive breast carcinomas from patients treated within the neoadjuvant GeparQuattro trial.
- Publication
Breast cancer research : BCR, 2013, Vol 15, Issue 1, pR11
- ISSN
1465-542X
- Publication type
Journal Article
- DOI
10.1186/bcr3384