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- Title
Effects of cyclin D<sub>1</sub> gene amplification and protein expression on time to recurrence in postmenopausal breast cancer patients treated with anastrozole or tamoxifen: a TransATAC study.
- Abstract
The article focuses on a study that distinguishes the relationship between CCND1 amplification and cyclin D1 protein expression and breast cancer recurrence among postmenopausal patients. The researchers examined a cohort of postmenopausal breast cancer patients randomised to receive adjuvant anastrozole or tamoxifen in the Arimidex, Tamoxifen, Alone or in Combination (ATAC) trial. It predicted poor clinical outcome in postmenopausal breast cancer patients treated with the drug.
- Publication
Breast Cancer Research, 2012, Vol 14, Issue 1, pR57
- ISSN
1465-5411
- Publication type
Academic Journal
- DOI
10.1186/bcr3161