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- Title
Landscape of somatic allelic imbalances and copy number alterations in HER2-amplified breast cancer.
- Authors
Staaf, Johan; Jönsson, Göran; Ringnér, Markus; Baldetorp, Bo; Borg, Ake
- Abstract
Human epidermal growth factor receptor 2 (HER2)-amplified breast cancer represents a clinically well-defined subgroup due to availability of targeted treatment. However, HER2-amplified tumors have been shown to be heterogeneous at the genomic level by genome-wide microarray analyses, pointing towards a need of further investigations for identification of recurrent copy number alterations and delineation of patterns of allelic imbalance.
- Publication
Breast cancer research : BCR, 2011, Vol 13, Issue 6, pR129
- ISSN
1465-542X
- Publication type
Journal Article
- DOI
10.1186/bcr3075