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- Title
Prognostic utility of the breast cancer index and comparison to Adjuvant! Online in a clinical case series of early breast cancer.
- Authors
Jankowitz, Rachel C; Cooper, Kristine; Erlander, Mark G; Ma, Xiao-Jun; Kesty, Nicole C; Li, Hongying; Chivukula, Mamatha; Brufsky, Adam
- Abstract
Breast Cancer Index (BCI) combines two independent biomarkers, HOXB13:IL17BR (H:I) and the 5-gene molecular grade index (MGI), that assess estrogen-mediated signalling and tumor grade, respectively. BCI stratifies early-stage estrogen-receptor positive (ER+), lymph-node negative (LN-) breast cancer patients into three risk groups and provides a continuous assessment of individual risk of distant recurrence. Objectives of the current study were to validate BCI in a clinical case series and to compare the prognostic utility of BCI and Adjuvant!Online (AO).
- Publication
Breast cancer research : BCR, 2011, Vol 13, Issue 5, pR98
- ISSN
1465-542X
- Publication type
Journal Article
- DOI
10.1186/bcr3038