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- Title
Mycophenolic acid counteracts B cell proliferation and plasmablast formation in patients with systemic lupus erythematosus.
- Authors
Eickenberg, Sebastian; Mickholz, Eva; Jung, Elisabeth; Nofer, Jerzy-Roch; Pavenstadt, Hermann J; Jacobi, Annett M
- Abstract
Clinical trials revealed a high efficacy of mycophenolate mofetil (MMF)in inducing and maintaining remission in patients with class III-V-lupus nephritis. Also extrarenal manifestations respond to MMF treatment. However, few attempts have been undertaken to delineate its mechanism of action in systemic lupus erythematosus (SLE) a disease characterized by enhanced B cell activation.
- Publication
Arthritis research & therapy, 2012, Vol 14, Issue 3, pR110
- ISSN
1478-6362
- Publication type
Journal Article
- DOI
10.1186/ar3835