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- Title
The neuropeptide neuromedin U promotes autoantibody-mediated arthritis.
- Authors
Rao, Sindhuja M; Auger, Jennifer L; Gaillard, Philippe; Weissleder, Ralph; Wada, Etsuko; Torres, Richard; Kojima, Masayasu; Benoist, Christophe; Mathis, Diane; Binstadt, Bryce A
- Abstract
Neuromedin U (NMU) is a neuropeptide with pro-inflammatory activity. The primary goal of this study was to determine if NMU promotes autoantibody-induced arthritis. Additional studies addressed the cellular source of NMU and sought to define the NMU receptor responsible for its pro-inflammatory effects.
- Publication
Arthritis research & therapy, 2012, Vol 14, Issue 1, pR29
- ISSN
1478-6362
- Publication type
Journal Article
- DOI
10.1186/ar3732