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- Title
Baseline predictors of response and discontinuation of tumor necrosis factor-alpha blocking therapy in ankylosing spondylitis: a prospective longitudinal observational cohort study.
- Authors
Arends, Suzanne; Brouwer, Elisabeth; van der Veer, Eveline; Groen, Henk; Leijsma, Martha K; Houtman, Pieternella M; Th A Jansen, Tim L; Kallenberg, Cees G M; Spoorenberg, Anneke
- Abstract
Identifying ankylosing spondylitis (AS) patients who are likely to benefit from tumor necrosis factor-alpha (TNF-α) blocking therapy is important, especially in view of the costs and potential side effects of these agents. Recently, the AS Disease Activity Score (ASDAS) has been developed to assess both subjective and objective aspects of AS disease activity. However, data about the predictive value of the ASDAS with respect to clinical response to TNF-α blocking therapy are lacking. The aim of the present study was to identify baseline predictors of response and discontinuation of TNF-α blocking therapy in AS patients in daily clinical practice.
- Publication
Arthritis research & therapy, 2011, Vol 13, Issue 3, pR94
- ISSN
1478-6362
- Publication type
Journal Article
- DOI
10.1186/ar3369