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- Title
Everolimus-induced human keratinocytes toxicity is mediated by STAT3 inhibition.
- Authors
Yamamoto, Kazuhiro; Uda, Atsushi; Mukai, Akira; Yamashita, Kazuhiko; Kume, Manabu; Makimoto, Hiroo; Bito, Toshinori; Nishigori, Chikako; Hirano, Takeshi; Hirai, Midori
- Abstract
Mammalian target of rapamycin (mTOR) inhibitors are associated with dermatological adverse events. The chief aim of this study was to examine the relation between the signal transducer and activator of transcription 3 (STAT3) protein and the dermatological adverse events associated with the mTOR inhibitor everolimus.
- Publication
Journal of experimental & clinical cancer research : CR, 2013, Vol 32, p83
- ISSN
1756-9966
- Publication type
Journal Article
- DOI
10.1186/1756-9966-32-83