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- Title
Fentanyl enhances the excitability of rapidly adapting receptors to cause cough via the enhancement of histamine release in the airways.
- Authors
Kamei, Junzo; Nakanishi, Yuki; Asato, Megumi; Ikeda, Hiroko
- Abstract
Although the mechanism of fentanyl-induced cough is unclear, several lines of evidence suggest that allergic mediators, such as histamine, may play a role in the production of fentanyl-induced coughs. The aim of this study was to explore the effects of fentanyl on cough sensitivity to inhaled citric acid and on histamine release in BALF in mice.
- Publication
Cough (London, England), 2013, Vol 9, Issue 1, p3
- ISSN
1745-9974
- Publication type
Journal Article
- DOI
10.1186/1745-9974-9-3