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- Title
Mechanical induction of cough in Idiopathic Pulmonary Fibrosis.
- Authors
Jones, Richard M; Hilldrup, Simon; Hope-Gill, Benjamin Dm; Eccles, Ronald; Harrison, Nicholas K
- Abstract
Patients with idiopathic pulmonary fibrosis (IPF) frequently develop a dry, irritating cough which often proves refractory to anti-tussive therapies. The precise pathogenetic mechanisms responsible for this cough are unknown. We hypothesised that changes in nerves modulating mechanical sensitivity in areas of interstitial fibrosis might lead to enhanced cough response to mechanical stimulation of the chest in IPF.
- Publication
Cough (London, England), 2011, Vol 7, p2
- ISSN
1745-9974
- Publication type
Journal Article
- DOI
10.1186/1745-9974-7-2