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- Title
Dexamethasone reduces emesis after major gastrointestinal surgery (DREAMS).
- Authors
Hamilton, Emma; Ravikumar, Reena; Bartlett, David; Hepburn, Elizabeth; Hwang, Mei-Ju; Mirza, Nazzia; Bahia, Sandeep S; Wilkey, Anthony; Bodenham Chilton, Helen; Handley, Kelly; Magill, Laura; Morton, Dion; West Midlands Research Collaborative
- Abstract
Postoperative nausea and vomiting is one of the most common complications affecting patients after surgery and causes significant morbidity and increased length of hospital stay. It is accepted that patients undergoing surgery on the bowel are at a higher risk. In the current era of minimally invasive colorectal surgery combined with enhanced recovery, reducing the incidence and severity of postoperative nausea and vomiting is particularly important. Dexamethasone is widely, but not universally used. It is known to improve appetite and gastric emptying, thus reduce vomiting. However, this benefit is not established in patients undergoing bowel surgery, and dexamethasone has possible side effects such as increased risk of wound infection and anastomotic leak that could adversely affect recovery.
- Publication
Trials, 2013, Vol 14, p249
- ISSN
1745-6215
- Publication type
Journal Article
- DOI
10.1186/1745-6215-14-249