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- Title
No association of xenotropic murine leukemia virus-related virus with prostate cancer or chronic fatigue syndrome in Japan.
- Authors
Furuta, Rika A; Miyazawa, Takayuki; Sugiyama, Takeki; Kuratsune, Hirohiko; Ikeda, Yasuhiro; Sato, Eiji; Misawa, Naoko; Nakatomi, Yasuhito; Sakuma, Ryuta; Yasui, Kazuta; Yamaguti, Kouzi; Hirayama, Fumiya
- Abstract
The involvement of xenotropic murine leukemia virus-related virus (XMRV) in prostate cancer (PC) and chronic fatigue syndrome (CFS) is disputed as its reported prevalence ranges from 0% to 25% in PC cases and from 0% to more than 80% in CFS cases. To evaluate the risk of XMRV infection during blood transfusion in Japan, we screened three populations--healthy donors (n = 500), patients with PC (n = 67), and patients with CFS (n = 100)--for antibodies against XMRV proteins in freshly collected blood samples. We also examined blood samples of viral antibody-positive patients with PC and all (both antibody-positive and antibody-negative) patients with CFS for XMRV DNA.
- Publication
Retrovirology, 2011, Vol 8, p20
- ISSN
1742-4690
- Publication type
Journal Article
- DOI
10.1186/1742-4690-8-20