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- Title
Current concepts regarding the HTLV-1 receptor complex.
- Authors
Ghez, David; Lepelletier, Yves; Jones, Kathryn S; Pique, Claudine; Hermine, Olivier
- Abstract
The identity of the Human T lymphotropic Virus type 1 (HTLV-1) receptor remained an unsolved puzzle for two decades, until the recent demonstration that three molecules, Glucose Transporter 1, Neuropilin-1 and Heparan Sulfate Proteoglycans are involved in HTLV-1 binding and entry. Despite these advances, several questions remain unanswered, including the precise role of each of these molecules during virus entry. In light of the most recent data, we propose a model of the HTLV-1 receptor complex and discuss its potential impact on HTLV-1 infection.
- Publication
Retrovirology, 2010, Vol 7, p99
- ISSN
1742-4690
- Publication type
Journal Article
- DOI
10.1186/1742-4690-7-99