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- Title
Proviral integrations and expression of endogenous avian leucosis virus during long term selection for high and low body weight in two chicken lines.
- Authors
Ka, Sojeong; Kerje, Susanne; Bornold, Lina; Liljegren, Ulrika; Siegel, Paul B; Andersson, Leif; Hallböök, Finn
- Abstract
Long-term selection (> 45 generations) for low or high juvenile body weight from a common founder population of White Plymouth Rock chickens has generated two extremely divergent lines, the LWS and HWS lines. In addition to a > 9-fold difference between lines for the selected trait, large behavioural and metabolic differences between the two lines evolved during the course of the selection. We recently compared gene expression in brain tissue from birds representing these lines using a global cDNA array analysis and the results showed multiple but small expression differences in protein coding genes. The main differentially expressed transcripts were endogenous retroviral sequences identified as avian leucosis virus subgroup-E (ALVE).
- Publication
Retrovirology, 2009, Vol 6, p68
- ISSN
1742-4690
- Publication type
Journal Article
- DOI
10.1186/1742-4690-6-68