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Title
Proteasome-independent degradation of HIV-1 in naturally non-permissive human placental trophoblast cells.
Authors
Ross, Anna Laura; Cannou, Claude; Barré-Sinoussi, Françoise; Menu, Elisabeth
Abstract
The human placenta-derived cell line BeWo has been demonstrated to be restrictive to cell-free HIV-1 infection. BeWo cells are however permissive to infection by VSV-G pseudotyped HIV-1, which enters cells by a receptor-independent mechanism, and to infection by HIV-1 via a cell-to-cell route.