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- Title
HIV-1 TAR miRNA protects against apoptosis by altering cellular gene expression.
- Authors
Klase, Zachary; Winograd, Rafael; Davis, Jeremiah; Carpio, Lawrence; Hildreth, Richard; Heydarian, Mohammad; Fu, Sidney; McCaffrey, Timothy; Meiri, Eti; Ayash-Rashkovsky, Mila; Gilad, Shlomit; Bentwich, Zwi; Kashanchi, Fatah
- Abstract
RNA interference is a gene regulatory mechanism that employs small RNA molecules such as microRNA. Previous work has shown that HIV-1 produces TAR viral microRNA. Here we describe the effects of the HIV-1 TAR derived microRNA on cellular gene expression.
- Publication
Retrovirology, 2009, Vol 6, p18
- ISSN
1742-4690
- Publication type
Journal Article
- DOI
10.1186/1742-4690-6-18