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- Title
Expression pattern analysis of transcribed HERV sequences is complicated by ex vivo recombination.
- Authors
Flockerzi, Aline; Maydt, Jochen; Frank, Oliver; Ruggieri, Alessia; Maldener, Esther; Seifarth, Wolfgang; Medstrand, Patrik; Lengauer, Thomas; Meyerhans, Andreas; Leib-Mösch, Christine; Meese, Eckart; Mayer, Jens
- Abstract
The human genome comprises numerous human endogenous retroviruses (HERVs) that formed millions of years ago in ancestral species. A number of loci of the HERV-K(HML-2) family are evolutionarily much younger. A recent study suggested an infectious HERV-K(HML-2) variant in humans and other primates. Isolating such a variant from human individuals would be a significant finding for human biology.
- Publication
Retrovirology, 2007, Vol 4, p39
- ISSN
1742-4690
- Publication type
Journal Article
- DOI
10.1186/1742-4690-4-39