We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Pathologic and biologic response to preoperative endocrine therapy in patients with ER-positive ductal carcinoma in situ.
- Authors
Chen, Yunn-Yi; DeVries, Sandy; Anderson, Joseph; Lessing, Juan; Swain, Rebecca; Chin, Koei; Shim, Veronica; Esserman, Laura J; Waldman, Frederic M; Hwang, E Shelley
- Abstract
Endocrine therapy is commonly recommended in the adjuvant setting for patients as treatment for ductal carcinoma in situ (DCIS). However, it is unknown whether a neoadjuvant (preoperative) anti-estrogen approach to DCIS results in any biological change. This study was undertaken to investigate the pathologic and biomarker changes in DCIS following neoadjuvant endocrine therapy compared to a group of patients who did not undergo preoperative anti-estrogenic treatment to determine whether such treatment results in detectable histologic alterations.
- Publication
BMC cancer, 2009, Vol 9, p285
- ISSN
1471-2407
- Publication type
Journal Article
- DOI
10.1186/1471-2407-9-285