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- Title
A proteomic strategy to identify novel serum biomarkers for liver cirrhosis and hepatocellular cancer in individuals with fatty liver disease.
- Authors
Gray, Joe; Chattopadhyay, Dipankar; Beale, Gary S; Patman, Gillian L; Miele, Luca; King, Barry P; Stewart, Stephen; Hudson, Mark; Day, Christopher P; Manas, Derek M; Reeves, Helen L
- Abstract
Non-alcoholic fatty liver disease (NAFLD) has a prevalence of over 20% in Western societies. Affected individuals are at risk of developing both cirrhosis and hepatocellular cancer (HCC). Presently there is no cost effective population based means of identifying cirrhotic individuals and even if there were, our ability to perform HCC surveillance in the at risk group is inadequate. We have performed a pilot proteomic study to assess this as a strategy for serum biomarker detection.
- Publication
BMC cancer, 2009, Vol 9, p271
- ISSN
1471-2407
- Publication type
Journal Article
- DOI
10.1186/1471-2407-9-271