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- Title
Modified FOLFOX-6 chemotherapy in advanced gastric cancer: Results of phase II study and comprehensive analysis of polymorphisms as a predictive and prognostic marker.
- Authors
Keam, Bhumsuk; Im, Seock-Ah; Han, Sae-Won; Ham, Hye Seon; Kim, Min A; Oh, Do-Youn; Lee, Se-Hoon; Kim, Jee Hyun; Kim, Dong-Wan; Kim, Tae-You; Heo, Dae Seog; Kim, Woo Ho; Bang, Yung-Jue
- Abstract
The objective of this study was to evaluate the efficacy and toxicity of infusional 5-fluorouracil (5-FU), folinic acid and oxaliplatin (modified FOLFOX-6) in patients with advanced gastric cancer (AGC), as first-line palliative combination chemotherapy. We also analyzed the predictive or prognostic value of germline polymorphisms of candidate genes associated with 5-FU and oxaliplatin.
- Publication
BMC cancer, 2008, Vol 8, p148
- ISSN
1471-2407
- Publication type
Journal Article
- DOI
10.1186/1471-2407-8-148