We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Expression of estrogen receptor beta in the breast carcinoma of BRCA1 mutation carriers.
- Authors
Litwiniuk, Maria M; Roznowski, Krzysztof; Filas, Violetta; Godlewski, Dariusz D; Stawicka, Małgorzata; Kaleta, Remigiusz; Breborowicz, Jan
- Abstract
Breast cancers (BC) in women carrying mutations in BRCA1 gene are more frequently estrogen receptor negative than the nonhereditary BC. Nevertheless, tamoxifen has been found to have a protective effect in preventing contralateral tumors in BRCA1 mutation carriers. The identification of the second human estrogen receptor, ERbeta, raised a question of its role in hereditary breast cancer. The aim of this study was to assess the frequency of ERalpha, ERbeta, PgR (progesterone receptor) and HER-2 expression in breast cancer patients with mutated BRCA1 gene and in the control group.
- Publication
BMC cancer, 2008, Vol 8, p100
- ISSN
1471-2407
- Publication type
Journal Article
- DOI
10.1186/1471-2407-8-100