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Title
Abnormal expression and processing of the proprotein convertases PC1 and PC2 in human colorectal liver metastases.
Authors
Tzimas, George N; Chevet, Eric; Jenna, Sarah; Nguyên, Duc Thang; Khatib, Abdel M; Marcus, Victoria; Zhang, Yi; Chrétien, Michel; Seidah, Nabil; Metrakos, Peter
Abstract
The family of proprotein convertases has been recently implicated in tumorigenesis and metastasis in animal models. However, these studies have not yet been completely corroborated in human tumors.