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- Title
Tumor classification: molecular analysis meets Aristotle.
- Authors
Berman, Jules J
- Abstract
Traditionally, tumors have been classified by their morphologic appearances. Unfortunately, tumors with similar histologic features often follow different clinical courses or respond differently to chemotherapy. Limitations in the clinical utility of morphology-based tumor classifications have prompted a search for a new tumor classification based on molecular analysis. Gene expression array data and proteomic data from tumor samples will provide complex data that is unobtainable from morphologic examination alone. The growing question facing cancer researchers is, "How can we successfully integrate the molecular, morphologic and clinical characteristics of human cancer to produce a helpful tumor classification?"
- Publication
BMC cancer, 2004, Vol 4, p10
- ISSN
1471-2407
- Publication type
Journal Article
- DOI
10.1186/1471-2407-4-10