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- Title
Profiling of normal and malignant breast tissue show CD44high/CD24low phenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers.
- Authors
Ghebeh, Hazem; Sleiman, Ghida Majed; Manogaran, Pulicat S; Al-Mazrou, Amer; Barhoush, Eman; Al-Mohanna, Falah H; Tulbah, Asma; Al-Faqeeh, Khalid; Adra, Chaker N
- Abstract
Accumulating evidence supports cancer to initiate and develop from a small population of stem-like cells termed as cancer stem cells (CSC). The exact phenotype of CSC and their counterparts in normal mammary gland is not well characterized. In this study our aim was to evaluate the phenotype and function of stem/progenitor cells in normal mammary epithelial cell populations and their malignant counterparts.
- Publication
BMC cancer, 2013, Vol 13, p289
- ISSN
1471-2407
- Publication type
Journal Article
- DOI
10.1186/1471-2407-13-289