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- Title
Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells.
- Abstract
The article discusses a study which investigated whether polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells. The study examined the expression of PLK1 mRNA in medulloblastoma tumor samples using microarray analysis. The study concluded that targeting PLK1 with small molecule inhibitors, in combination with radiation therapy, is a novel strategy in the treatment of medulloblastoma.
- Publication
BMC Cancer, 2012, Vol 12, Issue 1, p80
- ISSN
1471-2407
- Publication type
Academic Journal
- DOI
10.1186/1471-2407-12-80