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- Title
Role of plasma EBV DNA levels in predicting recurrence of nasopharyngeal carcinoma in a Western population.
- Authors
Ferrari, Daris; Codecà, Carla; Bertuzzi, Cecilia; Broggio, Francesca; Crepaldi, Francesca; Luciani, Andrea; Floriani, Irene; Ansarin, Mohssen; Chiesa, Fausto; Alterio, Daniela; Foa, Paolo
- Abstract
Loco-regionally advanced nasopharyngeal carcinomas can be cured by the combination of chemotherapy and radiotherapy. In Eastern countries, plasma levels of viral Epstein-Barr deoxyribonucleic acid (DNA) are accurate in predicting recurrence, but few data are available in Western populations. The aim of this prospective study was to evaluate the relationship between viral Epstein-Barr DNA copy numbers in plasma and the response rate, progression-free survival and overall survival in a cohort of Western patients with stage IIb-IVb nasopharyngeal cancer.
- Publication
BMC cancer, 2012, Vol 12, p208
- ISSN
1471-2407
- Publication type
Journal Article
- DOI
10.1186/1471-2407-12-208