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- Title
Nuclear expression of Rac1 in cervical premalignant lesions and cervical cancer cells.
- Abstract
The article discusses a study which analyzed the expression of the GTPases Rac1, RhoA, Cdc42, and the Rho-GEFs, Tiam1 and beta-Pix, in cervical pre-malignant lesions and cervical cancer cell lines. The study analyzed protein expression by immunochemistry on 102 cervical paraffin-embedded biopsies: 20 without Squamous Intraepithelial Lesions (SIL), 51 Low- grade SIL, and 31 High-grade SIL; and in cervical cancer cell lines C33A and SiHa, and non-tumorigenic HaCat cells.
- Publication
BMC Cancer, 2012, Vol 12, Issue 1, p116
- ISSN
1471-2407
- Publication type
Academic Journal
- DOI
10.1186/1471-2407-12-116