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- Title
Pharmacogenetic profiling and cetuximab outcome in patients with advanced colorectal cancer.
- Authors
Dahan, Laetitia; Norguet, Emmanuelle; Etienne-Grimaldi, Marie-Christine; Formento, Jean-Louis; Gasmi, Mohamed; Nanni, Isabelle; Gaudart, Jean; Garcia, Stéphane; Ouafik, L'Houcine; Seitz, Jean-François; Milano, Gérard
- Abstract
We analyzed the influence of 8 germinal polymorphisms of candidate genes potentially related to EGFR signalling (EGFR, EGF, CCND1) or antibody-directed cell cytotoxicity (FCGR2A and FCGR3A) on outcome of colorectal cancer (CRC) patients receiving cetuximab-based therapy.
- Publication
BMC cancer, 2011, Vol 11, p496
- ISSN
1471-2407
- Publication type
Journal Article
- DOI
10.1186/1471-2407-11-496