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- Title
Chemotherapy followed by surgery versus surgery alone in patients with resectable oesophageal squamous cell carcinoma: long-term results of a randomized controlled trial.
- Authors
Boonstra, Jurjen J; Kok, Tjebbe C; Wijnhoven, Bas Pl; van Heijl, Mark; van Berge Henegouwen, Mark I; Ten Kate, Fiebo Jw; Siersema, Peter D; Dinjens, Winand Nm; van Lanschot, Jan Jb; Tilanus, Hugo W; van der Gaast, Ate
- Abstract
This is a randomized, controlled trial of preoperative chemotherapy in patients undergoing surgery for oesophageal squamous cell carcinoma (OSCC). Patients were allocated to chemotherapy, consisting of 2-4 cycles of cisplatin and etoposide, followed by surgery (CS group) or surgery alone (S group). Initial results reported only in abstract form in 1997, demonstrated an advantage for overall survival in the CS group. The results of this trial have been updated and discussed in the timeframe in which this study was performed.
- Publication
BMC cancer, 2011, Vol 11, p181
- ISSN
1471-2407
- Publication type
Journal Article
- DOI
10.1186/1471-2407-11-181