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- Title
Characterisation of prostate cancer lesions in heterozygous Men1 mutant mice.
- Authors
Seigne, Christelle; Fontanière, Sandra; Carreira, Christine; Lu, Jieli; Tong, Wei-Ming; Fontanière, Bernard; Wang, Zhao-Qi; Zhang, Chang Xian; Frappart, Lucien
- Abstract
Mutations of the MEN1 gene predispose to multiple endocrine neoplasia type 1 (MEN1) syndrome. Our group and others have shown that Men1 disruption in mice recapitulates MEN1 pathology. Intriguingly, rare lesions in hormone-dependent tissues, such as prostate and mammary glands, were also observed in the Men1 mutant mice.
- Publication
BMC cancer, 2010, Vol 10, p395
- ISSN
1471-2407
- Publication type
Journal Article
- DOI
10.1186/1471-2407-10-395