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- Title
Retrocopy contributions to the evolution of the human genome.
- Authors
Baertsch, Robert; Diekhans, Mark; Kent, W James; Haussler, David; Brosius, Jürgen
- Abstract
Evolution via point mutations is a relatively slow process and is unlikely to completely explain the differences between primates and other mammals. By contrast, 45% of the human genome is composed of retroposed elements, many of which were inserted in the primate lineage. A subset of retroposed mRNAs (retrocopies) shows strong evidence of expression in primates, often yielding functional retrogenes.
- Publication
BMC genomics, 2008, Vol 9, p466
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-9-466