We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Sources of variation in baseline gene expression levels from toxicogenomics study control animals across multiple laboratories.
- Authors
Boedigheimer, Michael J; Wolfinger, Russell D; Bass, Michael B; Bushel, Pierre R; Chou, Jeff W; Cooper, Matthew; Corton, J Christopher; Fostel, Jennifer; Hester, Susan; Lee, Janice S; Liu, Fenglong; Liu, Jie; Qian, Hui-Rong; Quackenbush, John; Pettit, Syril; Thompson, Karol L
- Abstract
The use of gene expression profiling in both clinical and laboratory settings would be enhanced by better characterization of variance due to individual, environmental, and technical factors. Meta-analysis of microarray data from untreated or vehicle-treated animals within the control arm of toxicogenomics studies could yield useful information on baseline fluctuations in gene expression, although control animal data has not been available on a scale and in a form best served for data-mining.
- Publication
BMC genomics, 2008, Vol 9, p285
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-9-285