We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Mapping of transcription start sites of human retina expressed genes.
- Authors
Roni, Valeria; Carpio, Ronald; Wissinger, Bernd
- Abstract
The proper assembly of the transcriptional initiation machinery is a key regulatory step in the execution of the correct program of mRNA synthesis. The use of alternative transcription start sites (TSSs) provides a mechanism for cell and tissue specific gene regulation. Our knowledge of transcriptional initiation sequences in the human genome is limited despite the availability of the complete genome sequence. While genome wide experimental and bioinformatic approaches are improving our knowledge of TSSs, they lack information concerning genes expressed in a restricted manner or at very low levels, such as tissue specific genes.
- Publication
BMC genomics, 2007, Vol 8, p42
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-8-42