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- Title
The full-ORF clone resource of the German cDNA Consortium.
- Authors
Bechtel, Stephanie; Rosenfelder, Heiko; Duda, Anny; Schmidt, Christian Peter; Ernst, Ute; Wellenreuther, Ruth; Mehrle, Alexander; Schuster, Claudia; Bahr, Andre; Blöcker, Helmut; Heubner, Dagmar; Hoerlein, Andreas; Michel, Guenter; Wedler, Holger; Köhrer, Karl; Ottenwälder, Birgit; Poustka, Annemarie; Wiemann, Stefan; Schupp, Ingo
- Abstract
With the completion of the human genome sequence the functional analysis and characterization of the encoded proteins has become the next urging challenge in the post-genome era. The lack of comprehensive ORFeome resources has thus far hampered systematic applications by protein gain-of-function analysis. Gene and ORF coverage with full-length ORF clones thus needs to be extended. In combination with a unique and versatile cloning system, these will provide the tools for genome-wide systematic functional analyses, to achieve a deeper insight into complex biological processes.
- Publication
BMC genomics, 2007, Vol 8, p399
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-8-399