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- Title
CoryneRegNet: an ontology-based data warehouse of corynebacterial transcription factors and regulatory networks.
- Authors
Baumbach, Jan; Brinkrolf, Karina; Czaja, Lisa F; Rahmann, Sven; Tauch, Andreas
- Abstract
The application of DNA microarray technology in post-genomic analysis of bacterial genome sequences has allowed the generation of huge amounts of data related to regulatory networks. This data along with literature-derived knowledge on regulation of gene expression has opened the way for genome-wide reconstruction of transcriptional regulatory networks. These large-scale reconstructions can be converted into in silico models of bacterial cells that allow a systematic analysis of network behavior in response to changing environmental conditions.
- Publication
BMC genomics, 2006, Vol 7, p24
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-7-24