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- Title
Comparative genome analysis: selection pressure on the Borrelia vls cassettes is essential for infectivity.
- Authors
Glöckner, Gernot; Schulte-Spechtel, Ulrike; Schilhabel, Markus; Felder, Marius; Sühnel, Jürgen; Wilske, Bettina; Platzer, Matthias
- Abstract
At least three species of Borrelia burgdorferi sensu lato (Bbsl) cause tick-borne Lyme disease. Previous work including the genome analysis of B. burgdorferi B31 and B. garinii PBi suggested a highly variable plasmid part. The frequent occurrence of duplicated sequence stretches, the observed plasmid redundancy, as well as the mainly unknown function and variability of plasmid encoded genes rendered the relationships between plasmids within and between species largely unresolvable.
- Publication
BMC genomics, 2006, Vol 7, p211
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-7-211