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- Title
Transcriptome analysis of the parasite Encephalitozoon cuniculi: an in-depth examination of pre-mRNA splicing in a reduced eukaryote.
- Authors
Grisdale, Cameron J; Bowers, Lisa C; Didier, Elizabeth S; Fast, Naomi M
- Abstract
The microsporidian Encephalitozoon cuniculi possesses one of the most reduced and compacted eukaryotic genomes. Reduction in this intracellular parasite has affected major cellular machinery, including the loss of over fifty core spliceosomal components compared to S. cerevisiae. To identify expression changes throughout the parasite's life cycle and also to assess splicing in the context of this reduced system, we examined the transcriptome of E. cuniculi using Illumina RNA-seq.
- Publication
BMC genomics, 2013, Vol 14, p207
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-14-207