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Title
Altered gene expression profiles in the hippocampus and prefrontal cortex of type 2 diabetic rats.
Abstract
The article focuses on a study conducted to analyze gene expression profiles in type 2 diabetic rats' hippocampus and prefrontal cortex, which determined the complex role of insulin signaling in fine-tuning brain functions. In relation to neurotransmission, lipid metabolism, neuronal development, insulin secretion, oxidative damage and DNA repair, these gene lists proved to be partly overlapping and encompassed genes.