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- Title
Identification of common genetic modifiers of neurodegenerative diseases from an integrative analysis of diverse genetic screens in model organisms.
- Abstract
The article focuses on a study conducted to identify common genetic modifiers of neurodegenerative diseases, which found a significant number of overlapping regulators of neurodegenerative disease models. Using C. elegans as the baseline model organism, an integrated analysis was conducted. In expected pathways, involvement of ubiquitin-related enzymes and histone deacetylases of the common genetic regulators some such as chaperones was found.
- Publication
BMC Genomics, 2012, Vol 13, Issue 1, p71
- ISSN
1471-2164
- Publication type
Academic Journal
- DOI
10.1186/1471-2164-13-71