We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A novel method to discover fluoroquinolone antibiotic resistance (qnr) genes in fragmented nucleotide sequences.
- Authors
Boulund, Fredrik; Johnning, Anna; Pereira, Mariana Buongermino; Larsson, D G Joakim; Kristiansson, Erik
- Abstract
Broad-spectrum fluoroquinolone antibiotics are central in modern health care and are used to treat and prevent a wide range of bacterial infections. The recently discovered qnr genes provide a mechanism of resistance with the potential to rapidly spread between bacteria using horizontal gene transfer. As for many antibiotic resistance genes present in pathogens today, qnr genes are hypothesized to originate from environmental bacteria. The vast amount of data generated by shotgun metagenomics can therefore be used to explore the diversity of qnr genes in more detail.
- Publication
BMC genomics, 2012, Vol 13, p695
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-13-695