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- Title
Genomic variation in the vomeronasal receptor gene repertoires of inbred mice.
- Authors
Wynn, Elizabeth H; Sánchez-Andrade, Gabriela; Carss, Keren J; Logan, Darren W
- Abstract
Vomeronasal receptors (VRs), expressed in sensory neurons of the vomeronasal organ, are thought to bind pheromones and mediate innate behaviours. The mouse reference genome has over 360 functional VRs arranged in highly homologous clusters, but the vast majority are of unknown function. Differences in these receptors within and between closely related species of mice are likely to underpin a range of behavioural responses. To investigate these differences, we interrogated the VR gene repertoire from 17 inbred strains of mice using massively parallel sequencing.
- Publication
BMC genomics, 2012, Vol 13, p415
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-13-415