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- Title
Comparative genomics and transcriptomics of lineages I, II, and III strains of Listeria monocytogenes.
- Authors
Hain, Torsten; Ghai, Rohit; Billion, André; Kuenne, Carsten Tobias; Steinweg, Christiane; Izar, Benjamin; Mohamed, Walid; Mraheil, Mobarak Abu; Domann, Eugen; Schaffrath, Silke; Kärst, Uwe; Goesmann, Alexander; Oehm, Sebastian; Pühler, Alfred; Merkl, Rainer; Vorwerk, Sonja; Glaser, Philippe; Garrido, Patricia; Rusniok, Christophe; Buchrieser, Carmen; Goebel, Werner; Chakraborty, Trinad
- Abstract
Listeria monocytogenes is a food-borne pathogen that causes infections with a high-mortality rate and has served as an invaluable model for intracellular parasitism. Here, we report complete genome sequences for two L. monocytogenes strains belonging to serotype 4a (L99) and 4b (CLIP80459), and transcriptomes of representative strains from lineages I, II, and III, thereby permitting in-depth comparison of genome- and transcriptome -based data from three lineages of L. monocytogenes. Lineage III, represented by the 4a L99 genome is known to contain strains less virulent for humans.
- Publication
BMC genomics, 2012, Vol 13, p144
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-13-144