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- Title
Characterization of killer immunoglobulin-like receptor genetics and comprehensive genotyping by pyrosequencing in rhesus macaques.
- Authors
Moreland, Anna J; Guethlein, Lisbeth A; Reeves, R Keith; Broman, Karl W; Johnson, R Paul; Parham, Peter; O'Connor, David H; Bimber, Benjamin N
- Abstract
Human killer immunoglobulin-like receptors (KIRs) play a critical role in governing the immune response to neoplastic and infectious disease. Rhesus macaques serve as important animal models for many human diseases in which KIRs are implicated; however, the study of KIR activity in this model is hindered by incomplete characterization of KIR genetics.
- Publication
BMC genomics, 2011, Vol 12, p295
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-12-295