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- Title
Modulation of gene expression in heart and liver of hibernating black bears (Ursus americanus).
- Authors
Fedorov, Vadim B; Goropashnaya, Anna V; Tøien, Øivind; Stewart, Nathan C; Chang, Celia; Wang, Haifang; Yan, Jun; Showe, Louise C; Showe, Michael K; Barnes, Brian M
- Abstract
Hibernation is an adaptive strategy to survive in highly seasonal or unpredictable environments. The molecular and genetic basis of hibernation physiology in mammals has only recently been studied using large scale genomic approaches. We analyzed gene expression in the American black bear, Ursus americanus, using a custom 12,800 cDNA probe microarray to detect differences in expression that occur in heart and liver during winter hibernation in comparison to summer active animals.
- Publication
BMC genomics, 2011, Vol 12, p171
- ISSN
1471-2164
- Publication type
Journal Article
- DOI
10.1186/1471-2164-12-171